The goal of the global strategy is to reduce the burden of dengue. There are four dengue virus denv types denv1, denv2, denv3, and denv4, all of which are capable of inducing severe disease dengue hemorrhagic fever dhfdengue shock syndrome dss. Feb 16, 2018 dengue denggey fever is a mosquitoborne disease that occurs in tropical and subtropical areas of the world. Oregon, 20002017 dengue is a mosquitoborne viral infection. Dengue virus type 2 in travelers returning to japan from. A high incidence of severe disease has been reported for infection sequences with denv12, 32, 42, and. Your doctor will likely ask about your medical and travel history. Dengue knowledge for medical students and physicians. Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. The clinical features and laboratory results of dengueinfected adult patients admitted to the hospital during the 2017 outbreak were analyzed in this study. In 2017 as of epidemiological week 11, the region of americas have reported 50 172 cases of dengue fever, a reduction as compared with corresponding periods in previous years. Dengue fever is a virus transmitted to humans through bites from the aedes mosquito, a daybiting mosquito.
This disease used to be called breakbone fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Our primary outcomes were a prevalence of laboratory confirmed dengue infection among clinically suspected patients, b seroprevalence in the general population and c case fatality ratio among laboratory confirmed dengue patients. Dengue is a disease caused by any one of four closely related dengue viruses denv1, denv2, denv3, and denv4. Our findings indicate that casepatients 1 and 2 were infected with denv2 cosmopolitan genotype during the same period, suggesting that it might be the causative strain in the worstever outbreak of this disease in sri lanka. In children, overt disease is recognized clinically in perhaps 20 to 30% of second heterotypic dengue infections and severe disease in about 2% 12, 27, 28. This global strategy for dengue prevention and control, 20122020 aims to address this need. Dengue fever is a mosquitoborne virus disease that has rapidly spread to several regions in recent times. In november 2009, the world health organization who issued a new guideline that classifies symptomatic cases as dengue or severe dengue. Transmission from human to human is predominantly by the mosquito aedes aegypti, which bites in the daytime, is adapted to human habitats and has a preference for. Symptoms typically begin three to fourteen days after infection. For details of dengue disease features and pathogenesis, see my. During 20142017, the network of 52 virology laboratories tested more than 200,000 suspected dengue fever patients and 28% were laboratory confirmed. The dengue vaccine dilemma the lancet infectious diseases. The infecting dengue type interacting with age also controls disease severity.
The recent emergence and reemergence of viral infections transmitted by vectorszika, chikungunya, dengue, japanese encephalitis, west nile, yellow fever and othersis a cause for international concern. Healthrelated quality of life after dengue fever, morelos. Nov 09, 2012 symptoms include fever, headache, muscle and joint pains, and a characteristic skin rash that is similar to measles. We searched for studies published until 2017 reporting the incidence, the prevalence or case fatality of dengue in india. Dengue is transmitted principally by aedes aegypti yellow fever mosquito and aedes albopictus asian tiger mosquito. Both viruses can cause severe diseases in humans with catastrophic sequelae. Dengue and its severe forms, namely, dengue haemorrhagic fever dhf and dengue shock.
A severe form of dengue fever, also called dengue hemorrhagic fever, can cause severe bleeding, a sudden drop in blood pressure shock and death. Dengue hemorrhagic feverdengue shock syndrome dhfdss is the most severe form of dengue disease and is characterized by vascular leakage, hemorrhagic manifestations, thrombocytopenia, and. If you think you have dengue pdf icon pdf 1 page see a healthcare provider if you develop a fever or have symptoms of dengue. Be sure to describe international trips in detail, including the countries you visited and the dates. Dengue hemorrhagic fever is a rare but more severe form of dengue infection that can be fatal if not recognized and treated with supportive care. The highest numbers of dengue cases were reported during the 29th week of 2017. Before you travel, find countryspecific travel information to help you plan and pack.
Dengue denggey fever is a mosquitoborne disease that occurs in tropical and subtropical areas of the world. In this outbreak, little is known about the causative virus type. Forty percent of the worlds population, about 3 billion people, live in areas with a risk of dengue. Patients with suspected dengue infection were classified further into 2 groups, dengue fever probable dengue, dengue with warning signs and severe dengue. Dengue occurs in many tropical and subtropical areas of the world, particularly subsaharan africa, the middle east, southeast asia, and central and south america. Health experts have known about dengue fever for more than 200 years.
Dengue is a viral disease transmitted by mosquitoes especially aedes aegypti and is widely distributed throughout the tropics and subtropics. Epidemiology of dengue fever in india, based on laboratory. Apr 12, 2019 for 2017, 27 countries reported 2 026 travelassociated cases of dengue fever, of which 1 818 89. The study all study participants signed informed consent forms. The pdf version will be available on the who searo website.
Dengue viruses are spread to people through the bite of an infected aedes species ae. The objective of this study is to assess the clinical profile of the dengue infection in children less than 15 years of age and to evaluate the outcomes of dengue fever from march 2017 to july. Antibodydependent enhancement of severe dengue disease in. Number of reported cases of dengue and severe dengue sd in the americas, epidemiological week 11 2017 pdf, 61kb. In this study, we sequenced 114 complete genomes of denv14 from 20 to 2017 and it provided a huge support for the research of dengue fever in guangdong, china. The highest rates in both men and women were 2544 years of age. Dengue and dengue haemorrhagic fever world health organization. The objective of the bulletin is to disseminate updated information on the current status of dengue fever dengue haemorrhagic fever infection, changing.
In the meantime, denv14 coexisted in guangdong province, especially in the pearl river delta area, and this was in agreement with earlier reports 26. The ethics committee of the national institute of public health project nos. Second heterotypic dengue disease has been observed in 12 sequences 19. Clinical findings include nausea, vomiting, rash, aches and pains, a positive tourniquet test, leukopenia. Sporadic autochthonous cases, or small clusters, of dengue fever. Jul 31, 2019 as children age, disease response, particularly after puberty, becomes more adultlike. Dengue fever is a disease spread by the aedes aegypti mosquito and caused by one of four dengue viruses that are closely related. Uncertainty in burden estimates, however, challenges policy makers ability to set priorities, allocate resources, and plan for interventions. Incidence of cryptosporidiosis by county of residence. There are four dengue virus denv types denv1, denv2, denv3, and denv4, all of which are capable of inducing severe disease dengue hemorrhagic fever dhf dengue shock syndrome dss. Dengue outbreaks are occurring in many countries of the word in the americas, africa, the middle east, asia, and the pacific islands. Dengue is a mosquitoborne flavivirus found in tropical and subtropical regions of the world, mostly in urban and semiurban settings.
Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of climate. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. The outbreak situation in 2017 warranted extensive and regular removal of possible mosquito breeding sites from the environment, along with strengthened patient education on management of fever which resulted in a relatively low mortality. Epidemiological and clinical features of dengue infection. We recruited participants with dengue from inpatient and outpatient facilities in morelos, mexico, during 20162017. Anyone who lives in or travels to an area with risk of dengue is at risk for infection. The objective of the bulletin is to disseminate updated information on the current status of dengue feverdengue haemorrhagic fever infection, changing. Nov 17, 2017 dengue fever is caused by a mosquitotransmitted flavivirus resembling zika virus. Dengue is a vectorborne viral infection and a globally important public health problem. In adults, primary dengue 1 and 3 infections result in high rates of classic dengue fever but dengue 2 and 4 infections cause milder disease and are often inapparent 12, 25. In affected regions such as asia and latin america, severe dengue is a leading cause of hospitalization and. A 2016 study estimated nearly 60 million symptomatic dengue cases worldwide every year estimates including asymptomatic cases are at least six times higher, resulting in about 10 000 deaths. Dengue fever df is the fastest emerging arboviral infection spread by aedes aegypti mosquitoes with major public health consequences for millions of people around the world, and in particular the southeast asia and asiapacific regions of the world health organization who. Dengue hemorrhagic fever dhf is a severe form of dengue fever.
In a small proportion of cases, the disease develops into severe dengue, also. Between january 2014 and december 2017, the 52 laboratories in vrdln tested 211,432 suspected dengue fever patients for laboratory confirmation of dengue fever. Local transmission of dengue fever in france and spain. The aedes aegypti mosquito is the primary vector of dengue. Using as examples zika, chikungunya and dengue, we summarise current knowledge on characteristics of the viruses and their transmission, clinical. Dengue is the most common mosquitotransmitted viral infectious disease. Symptoms include fever, headache, muscle and joint pains, and a characteristic skin rash that is similar to measles. The illness may progress to dengue hemorrhagic fever dhf.
However, the number of patients with dengue fever has increased drastically during the current and largest outbreak, during januaryjuly 2017, when 90,000 patients were reported in sri lanka, particularly in colombo. Dengue chapter 4 2020 yellow book travelers health. It is the fastest spreading vectorborne viral disease and is now endemic in over 100 countries, resulting in 40% of the worlds population living in an area at risk for dengue. Dengue bulletin dengue volume 39, december 2016 bulletin issn 02508362 issn 02508362 who the who regional office for southeast asia publish the annual dengue bulletin. Mild dengue fever causes a high fever, rash, and muscle and joint pain.
Dengue is common in more than 100 countries around the world. Dengue is often a leading cause of illness in areas. The disease is often diagnosed incorrectly because the symptoms are similar to influenza and other viruses. The disease is limited primarily to the tropics and subtropics, although imported cases occasionally occur. Pdf global epidemiology of dengue hemorrhagic fever. Dengue virus cannot be transmitted from person to person. During the year 2017 a total of 186,101 suspected dengue cases were reported and as of 24 may 2018 a total of 19,459 suspected dengue cases were reported to the epidemiology unit of the ministry. Symptoms include severe abdominal pain, vomiting, diarrhea, convulsions, bruising, and uncontrolled bleeding. Dengue fever is a mosquitoborne tropical disease caused by the dengue virus. It is caused by a flavivirus the same genus as west nile, zika and yellow fever viruses. Complications can lead to circulatory system failure and shock, and can be fatal also known as dengue shock syndrome. Dengue viruses 1 to 4 denv14 are mosquitoborne flaviviruses that cause 50 to 100 million cases of dengue fever df and 500,000 hospitalizations annually 1, 2. Treat the symptoms of dengue and see your healthcare provider.
Total of 51659 suspected dengue cases for the year 2018 and 18835 suspected dengue cases were reported to the epidemiology unit from all over the island from january 2020 to up to now. Clinical and laboratory diagnosis of dengue virus infection. Vdh chikungunya, dengue and zika virus infections cheat sheet for healthcare providers october 24, 2017 characteristics chikungunya virus chikv dengue virus denv zika virus zikv comments or additional information incubation period 37 days range 112 days 410 days range 314 days range 314 days signs and symptoms. The who regional office for southeast asia publish dengue. The viruses that cause dengue fever are related to those that. While dengue positivity was high in all age groups, most laboratory confirmed patients were older than 20 years. Dengue is a mosquitoborne disease caused by any one of four closely related dengue viruses. Dengue classically presents with high fever, headache, body aches, exanthem, and generalized lymphadenopathy. These mosquitoes are not native to california, but infestations have been identified in multiple counties in california pdf. Genomic epidemiological characteristics of dengue fever in. Dengue virus type 2 in travelers returning to japan from sri. These viruses are related to the viruses that cause. Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever vii dengue fever is the fastest emerging arboviral infection spread by aedes mosquitoes with major public health consequences in over 100 tropical and subtropical countries in southeast asia, the western pacific and south and central america.
For 2017, 27 countries reported 2 026 travelassociated cases of dengue fever, of which 1 818 89. Since the second edition of dengue haemorrhagic fever. Feb 16, 2018 diagnosing dengue fever can be difficult, because its signs and symptoms can be easily confused with those of other diseases such as malaria, leptospirosis and typhoid fever. The western pacific region has reported dengue outbreaks in several member states in the pacific, as well as the circulation of denv1 and denv2 serotypes. In a small proportion of cases the disease develops into the lifethreatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where. Disease burden of dengue fever and dengue haemorrhagic fever 3.