Dengue denggey fever is a mosquitoborne disease that occurs in tropical and subtropical areas of the world. The objective of this study is to assess the clinical profile of the dengue infection in children less than 15 years of age and to evaluate the outcomes of dengue fever from march 2017 to july. In children, overt disease is recognized clinically in perhaps 20 to 30% of second heterotypic dengue infections and severe disease in about 2% 12, 27, 28. In 2017 as of epidemiological week 11, the region of americas have reported 50 172 cases of dengue fever, a reduction as compared with corresponding periods in previous years. Between january 2014 and december 2017, the 52 laboratories in vrdln tested 211,432 suspected dengue fever patients for laboratory confirmation of dengue fever.
The goal of the global strategy is to reduce the burden of dengue. In this outbreak, little is known about the causative virus type. Dengue is transmitted principally by aedes aegypti yellow fever mosquito and aedes albopictus asian tiger mosquito. For details of dengue disease features and pathogenesis, see my. Dengue is a vectorborne viral infection and a globally important public health problem. A high incidence of severe disease has been reported for infection sequences with denv12, 32, 42, and.
A severe form of dengue fever, also called dengue hemorrhagic fever, can cause severe bleeding, a sudden drop in blood pressure shock and death. Dengue hemorrhagic feverdengue shock syndrome dhfdss is the most severe form of dengue disease and is characterized by vascular leakage, hemorrhagic manifestations, thrombocytopenia, and. Dengue hemorrhagic fever is a rare but more severe form of dengue infection that can be fatal if not recognized and treated with supportive care. Dengue pronounced dengee fever is a painful, debilitating mosquitoborne disease caused by any one of four closely related dengue viruses. Dengue chapter 4 2020 yellow book travelers health. This global strategy for dengue prevention and control, 20122020 aims to address this need. Dengue fever is a disease spread by the aedes aegypti mosquito and caused by one of four dengue viruses that are closely related. The aedes aegypti mosquito is the primary vector of dengue. Number of reported cases of dengue and severe dengue sd in the americas, epidemiological week 11 2017 pdf, 61kb. Patients with suspected dengue infection were classified further into 2 groups, dengue fever probable dengue, dengue with warning signs and severe dengue.
Dengue is a viral disease transmitted by mosquitoes especially aedes aegypti and is widely distributed throughout the tropics and subtropics. Healthrelated quality of life after dengue fever, morelos. Dengue is the most common mosquitotransmitted viral infectious disease. Dengue outbreaks are occurring in many countries of the word in the americas, africa, the middle east, asia, and the pacific islands. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. The highest numbers of dengue cases were reported during the 29th week of 2017. Dengue and dengue haemorrhagic fever world health organization.
In the meantime, denv14 coexisted in guangdong province, especially in the pearl river delta area, and this was in agreement with earlier reports 26. Transmission from human to human is predominantly by the mosquito aedes aegypti, which bites in the daytime, is adapted to human habitats and has a preference for. The pdf version will be available on the who searo website. Complications can lead to circulatory system failure and shock, and can be fatal also known as dengue shock syndrome. Dengue is often a leading cause of illness in areas. Both viruses can cause severe diseases in humans with catastrophic sequelae. Your doctor will likely ask about your medical and travel history. We searched for studies published until 2017 reporting the incidence, the prevalence or case fatality of dengue in india. Oregon, 20002017 dengue is a mosquitoborne viral infection. Dengue is a febrile illness caused by a flavivirus transmitted by aedes aegypti or aedes albopictus mosquitoes while taking a blood meal. The infecting dengue type interacting with age also controls disease severity.
Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of climate. Our primary outcomes were a prevalence of laboratory confirmed dengue infection among clinically suspected patients, b seroprevalence in the general population and c case fatality ratio among laboratory confirmed dengue patients. In this study, we sequenced 114 complete genomes of denv14 from 20 to 2017 and it provided a huge support for the research of dengue fever in guangdong, china. Dengue virus type 2 in travelers returning to japan from sri. Dengue fever is a mosquitoborne tropical disease caused by the dengue virus.
Dengue is a disease caused by any one of four closely related dengue viruses denv1, denv2, denv3, and denv4. There are four dengue virus denv types denv1, denv2, denv3, and denv4, all of which are capable of inducing severe disease dengue hemorrhagic fever dhfdengue shock syndrome dss. Dengue occurs in many tropical and subtropical areas of the world, particularly subsaharan africa, the middle east, southeast asia, and central and south america. An estimated 500 000 people with severe dengue require hospitalization each year, and about 2.
However, the number of patients with dengue fever has increased drastically during the current and largest outbreak, during januaryjuly 2017, when 90,000 patients were reported in sri lanka, particularly in colombo. Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. Sporadic autochthonous cases, or small clusters, of dengue fever. It is caused by a flavivirus the same genus as west nile, zika and yellow fever viruses. Incidence of cryptosporidiosis by county of residence. Health experts have known about dengue fever for more than 200 years. The objective of the bulletin is to disseminate updated information on the current status of dengue feverdengue haemorrhagic fever infection, changing.
If you think you have dengue pdf icon pdf 1 page see a healthcare provider if you develop a fever or have symptoms of dengue. The recent emergence and reemergence of viral infections transmitted by vectorszika, chikungunya, dengue, japanese encephalitis, west nile, yellow fever and othersis a cause for international concern. We recruited participants with dengue from inpatient and outpatient facilities in morelos, mexico, during 20162017. There are four dengue virus denv types denv1, denv2, denv3, and denv4, all of which are capable of inducing severe disease dengue hemorrhagic fever dhf dengue shock syndrome dss. Total of 51659 suspected dengue cases for the year 2018 and 18835 suspected dengue cases were reported to the epidemiology unit from all over the island from january 2020 to up to now. Jul 31, 2019 as children age, disease response, particularly after puberty, becomes more adultlike. The western pacific region has reported dengue outbreaks in several member states in the pacific, as well as the circulation of denv1 and denv2 serotypes. The study all study participants signed informed consent forms. Epidemiological and clinical features of dengue infection.
Dengue is common in more than 100 countries around the world. This disease used to be called breakbone fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Using as examples zika, chikungunya and dengue, we summarise current knowledge on characteristics of the viruses and their transmission, clinical. The clinical features and laboratory results of dengueinfected adult patients admitted to the hospital during the 2017 outbreak were analyzed in this study. The ethics committee of the national institute of public health project nos. The highest rates in both men and women were 2544 years of age. The who regional office for southeast asia publish dengue. It has been suspected in humans, and shown in animal models, that the hosts immune responses can make disease worse. Dengue hemorrhagic fever dhf is a severe form of dengue fever.
Apr 12, 2019 for 2017, 27 countries reported 2 026 travelassociated cases of dengue fever, of which 1 818 89. Dengue viruses are spread to people through the bite of an infected aedes species ae. Mild dengue fever causes a high fever, rash, and muscle and joint pain. Symptoms typically begin three to fourteen days after infection. These mosquitoes are not native to california, but infestations have been identified in multiple counties in california pdf. Anyone who lives in or travels to an area with risk of dengue is at risk for infection. The disease is limited primarily to the tropics and subtropics, although imported cases occasionally occur. The ministry of health of sri lanka reported 93,322 dengue fever cases, including 250 deaths, as of july 17, 2017. These viruses are related to the viruses that cause. The illness may progress to dengue hemorrhagic fever dhf.
The dengue vaccine dilemma the lancet infectious diseases. Feb 16, 2018 dengue denggey fever is a mosquitoborne disease that occurs in tropical and subtropical areas of the world. While dengue positivity was high in all age groups, most laboratory confirmed patients were older than 20 years. Dengue is a mosquitoborne disease caused by any one of four closely related dengue viruses. In a small proportion of cases, the disease develops into severe dengue, also. Dengue virus type 2 in travelers returning to japan from. Clinical findings include nausea, vomiting, rash, aches and pains, a positive tourniquet test, leukopenia. Dengue classically presents with high fever, headache, body aches, exanthem, and generalized lymphadenopathy.
Antibodydependent enhancement of severe dengue disease in. Nov 09, 2012 symptoms include fever, headache, muscle and joint pains, and a characteristic skin rash that is similar to measles. Disease burden of dengue fever and dengue haemorrhagic fever 3. Dengue and its severe forms, namely, dengue haemorrhagic fever dhf and dengue shock. For 2017, 27 countries reported 2 026 travelassociated cases of dengue fever, of which 1 818 89. Dengue virus cannot be transmitted from person to person. Our findings indicate that casepatients 1 and 2 were infected with denv2 cosmopolitan genotype during the same period, suggesting that it might be the causative strain in the worstever outbreak of this disease in sri lanka. Dengue viruses 1 to 4 denv14 are mosquitoborne flaviviruses that cause 50 to 100 million cases of dengue fever df and 500,000 hospitalizations annually 1, 2. The objective of the bulletin is to disseminate updated information on the current status of dengue fever dengue haemorrhagic fever infection, changing. Dengue is a mosquitoborne flavivirus found in tropical and subtropical regions of the world, mostly in urban and semiurban settings.
The outbreak situation in 2017 warranted extensive and regular removal of possible mosquito breeding sites from the environment, along with strengthened patient education on management of fever which resulted in a relatively low mortality. Forty percent of the worlds population, about 3 billion people, live in areas with a risk of dengue. In affected regions such as asia and latin america, severe dengue is a leading cause of hospitalization and. Dengue fever is a mosquitoborne virus disease that has rapidly spread to several regions in recent times. Epidemiology of dengue fever in india, based on laboratory. Pdf global epidemiology of dengue hemorrhagic fever. Be sure to describe international trips in detail, including the countries you visited and the dates. Uncertainty in burden estimates, however, challenges policy makers ability to set priorities, allocate resources, and plan for interventions. In november 2009, the world health organization who issued a new guideline that classifies symptomatic cases as dengue or severe dengue. Dengue knowledge for medical students and physicians. During 20142017, the network of 52 virology laboratories tested more than 200,000 suspected dengue fever patients and 28% were laboratory confirmed. Symptoms include severe abdominal pain, vomiting, diarrhea, convulsions, bruising, and uncontrolled bleeding. Local transmission of dengue fever in france and spain.
It is the fastest spreading vectorborne viral disease and is now endemic in over 100 countries, resulting in 40% of the worlds population living in an area at risk for dengue. Clinical and laboratory diagnosis of dengue virus infection. Genomic epidemiological characteristics of dengue fever in. During the year 2017 a total of 186,101 suspected dengue cases were reported and as of 24 may 2018 a total of 19,459 suspected dengue cases were reported to the epidemiology unit of the ministry. For 2017, 27 countries reported 2 026 travel associated cases of dengue fever, of which 1 818 89.
Dengue fever df is the fastest emerging arboviral infection spread by aedes aegypti mosquitoes with major public health consequences for millions of people around the world, and in particular the southeast asia and asiapacific regions of the world health organization who. Second heterotypic dengue disease has been observed in 12 sequences 19. The viruses that cause dengue fever are related to those that. Before you travel, find countryspecific travel information to help you plan and pack. Dengue begins abruptly after an incubation period of 57 days range, 310 days, and the course follows 3 phases. In a small proportion of cases the disease develops into the lifethreatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where. Dengue chapter 4 2020 yellow book travelers health cdc. A 2016 study estimated nearly 60 million symptomatic dengue cases worldwide every year estimates including asymptomatic cases are at least six times higher, resulting in about 10 000 deaths. Dengue fever is a virus transmitted to humans through bites from the aedes mosquito, a daybiting mosquito. Feb 16, 2018 diagnosing dengue fever can be difficult, because its signs and symptoms can be easily confused with those of other diseases such as malaria, leptospirosis and typhoid fever. Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever vii dengue fever is the fastest emerging arboviral infection spread by aedes mosquitoes with major public health consequences in over 100 tropical and subtropical countries in southeast asia, the western pacific and south and central america. Dengue bulletin dengue volume 39, december 2016 bulletin issn 02508362 issn 02508362 who the who regional office for southeast asia publish the annual dengue bulletin. The disease is often diagnosed incorrectly because the symptoms are similar to influenza and other viruses.